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Contents Review, 44 Article(s)
Review of crosstalk between pixels in division of focal plane polarization camera
Wei-qi JIN, Jia-an XUE, Su QIU, Lin LUO, and Qi-wei LIU

Division of focal plane polarization camera is a widely used integrated polarization imaging system. Crosstalk between pixels of the micro-polarizer arrays (MPAs) is the unique interference factor in such system, and its crosstalk light intensity varies with the polarization characteristics of the incident light, bringing errors to the measurement of the target’s polarization information. This paper reviews the development of polarization crosstalk models and summarizes all the factors affecting crosstalk identified in relevant researchs. Taking sensor parameters and optical system parameters as key factors, this paper discusses the cause-effect model of crosstalk in cameras and its relation to temporal noise. It analyzes the results of parameter changes caused by crosstalk, primarily summarizing the crosstalk’s factor correlation, experimental repeatability, error randomness and parameter calibration. Finally, this paper prospects the future development trends of crosstalk models.

Chinese Optics
Jul. 15, 2025, Vol. 18 Issue 4 725 (2025)
Research progress of space laser communication networking technology
Zhi LIU, Qing-fang JIANG, Shu-tong LIU, Shao-qian TIAN, Ling-yun ZHU, Xian-zhu LIU, Jia-xin YU, Jian-tong ZHAO, Hai-feng YAO, and Ke-yan DONG

Laser communication utilizes light waves as the transmission medium. It offers many advantages, including high data rates, expansive bandwidth, compactness, robust interference resistance, and superior confidentiality. It has the critical capability to enable high-speed transmission and secure operation of space information networks. Prominent research institutions have committed to studying a series of challenges that need to be solved in the process of networking laser communication technology, including point-to-multipoint simultaneous laser communication, all-optical switching and forwarding of multi-channel signals within nodes, node dynamic random access, and network topology design. Numerous demonstration and verification experiments have been conducted, with a subset of these research results finding practical applications. Based on the analysis and discussion of space laser communication networking technology, this paper summarizes the development of laser communication networking technology both domestically and internationally, focusing on the application of laser communication networking technology in the fields of satellite constellations, satellite relays, and aviation networks. Furthermore, it presents a review of pertinent domestic research methodologies, experimental validations, and technical solutions. Finally, it predicts the development trend of laser communication networking technology and applications.

Chinese Optics
May. 15, 2025, Vol. 18 Issue 3 429 (2025)
Rubidium atomic optical frequency standard based on two-photon transition
Jiong-yang ZHANG, Hao ZHAI, Ji WANG, Yu-hua XIAO, Hu DAI, Ji-qing LIAN, Shi-yu YANG, Jiang CHEN, and Zhi-dong LIU

The optical frequency standard based on two-photon transition is expected to become a practical miniaturized optical frequency standard due to its significant advantages such as high stability, good reproducibility and easy miniaturization. In this paper, the basic principle of two-photon transition is briefly described, and the research status and progress of rubidium atomic optical frequency standards based on two-photon transition at home and abroad are introduced. Finally, it is concluded that the future development trends of rubidium atomic optical frequency standards based on two-photon transition are system miniaturization, performance improvement, integrated application and engineering.

Chinese Optics
May. 15, 2025, Vol. 18 Issue 3 415 (2025)
Advances in data simulation for space-based situational awareness
Xiu-juan LUO, and Wei HAO

The data simulation for Space Situational Awareness (SSA) can provide critical data support for the development, testing, and validation of space surveillance equipment and situational awareness algorithms (including detection, tracking, recognition, and characterization of space object), playing a significant role in building SSA capabilities. Taking the optical data simulation for space-based situational awareness as the research subject, the purpose and main research content of SSA data simulation are presented, and the typical research methods and processes of SSA optical imaging simulation are set forth. The current research status and progress in domestic and foreign related research are introduced, covering the imaging modeling and simulation achievements of different optical sensing systems such as binocular vision sensors, LiDAR, infrared sensors, visible light telescopes, and star trackers. The development trend of SSA data simulation research is analyzed, providing reference for future research ideas and approaches of SSA data simulation.

Chinese Optics
Jul. 15, 2024, Vol. 17 Issue 3 501 (2024)
A review of the effect of GaN-Based Micro-LED sidewall on external quantum efficiency and sidewall treatment techniques
Hai KUANG, Zhen HUANG, Zhi-hua XIONG, and Li LIU

Micro-LEDs offers the benefits of high brightness, high response frequency, and low power consumption, making them an attractive candidate for future display technologies and Visible Light Communication (VLC) systems. Nonetheless, their low External Quantum Efficiency (EQE) currently impedes their scaled mass production and further applications. In order to break through the bottleneck of low EQE, we conducted an analysis of Micro-LED external quantum efficiency’s contributing factors. The influencing factors for EQE are analyzed. It is concluded that the carrier loss and non-radiative recombination caused by sidewall defects are the main reasons for the decrease in EQE. In addition, we summarized the impact of sidewall defects on carrier transport and composites, and we also reviewed the commonly used sidewall treatment technology and repair methods, and pointed out that the existing sidewall treatment methods are helpful but insufficient for improving EQE, and the mechanism of carrier interaction with sidewall defects is not very clear. It is suggested to carry out a thorough and systematic study on the types and distribution of sidewall defects, the mechanism of carrier and sidewall defects, and the defect repair mode in the sidewall treatment process. Finally, future development trends are projected. This paper offers design ideas and theoretical foundations to enhance the external quantum efficiency and accelerate the process of commercialization and mass production of Micro-LEDs.

Chinese Optics
Nov. 15, 2023, Vol. 16 Issue 6 1305 (2023)
Advances in optical fiber tweezer technology based on hetero-core fiber
Hong LI, Ying-xin ZHU, Ya-ni ZHOU, Hai-bo WANG, Ming-li DONG, and Lian-qing ZHU

Optical fiber tweezers are widely used in biochemical analysis, life sciences, and other fields due to their simple structure, flexible operation, and compact size. The hetero-core structure of the optical fiber probe possesses inherent advantages in near-field evanescent wave optical trapping force, core beam coupling transmission, and cross-synergistic application of microfluidic technology, which can realize the functions of cell and subcellular particle collection and transportation, and can significantly improve the three-dimensional particle trapping capability as well as dynamic manipulation level. In this paper, the structural characteristics and application technology research progress of optical fiber tweezers based on different core structures are reviewed. This paper sorts and compares key technologies, including probe preparation, laser source, and coupling mode, in hetero-core optical fiber tweezers systems. It also summarizes and provides a perspective on the role and development of hetero-core fibers with different structures in optical fiber tweezers.

Chinese Optics
Nov. 15, 2023, Vol. 16 Issue 6 1293 (2023)
Development and prospects of enhanced absorption spectroscopy
Yi-jie REN, Chang-xiang YAN, and Jia-wei XU

Optical path absorption spectroscopy is an important branch of absorption spectroscopy. In recent years, there has been a proliferation of optical path absorption spectroscopy techniques based on different light source technologies, absorption cavity technologies, and detection methods. As the demands on detection sensitivity and absorption optical path length increased, optical path absorption spectroscopy techniques based on the principle of enhanced absorption emerged, including integrated cavity spectroscopy (ICOS), cavity-enhanced absorption spectroscopy (CEAS) and cavity ring-down spectroscopy (CRDS). Enhanced absorption spectroscopy is advantageous for its high spectral resolution, high sensitivity, fast response time, and portability, but it presently lacks a unified concept and clear classification criteria. This paper compares the development history of absorption spectroscopy techniques and clarifies the concept of their multi-optical path. Based on whether resonant absorption occurs in the absorption cavity, the concept of absorption spectroscopy techniques based on resonance is proposed, and the current research status of resonant absorption spectroscopy techniques is analyzed and summarized, and the applications of this technique in various fields are outlined. Finally, the future development of key technologies in resonance absorption spectroscopy is envisioned.

Chinese Optics
Nov. 15, 2023, Vol. 16 Issue 6 1273 (2023)
Review of the cavity-design of high-energy thin-disk laser multi-pass amplifiers
Yi CHEN, Jun-jie SUN, Jing-hua YU, Zhi-huan YAO, Yi-wen ZHANG, De-yang YU, Yang HE, Kuo ZHANG, Qi-kun PAN, and Fei CHEN

In order to clarify the cavity design methods of thin-disk multi-pass amplifiers, we summarize the different types of thin-disk multi-pass amplifiers and concludes that there are four fundamental design concepts: (1) 4f relay imaging, (2) resonant cavity design/optical Fourier transform, (3) near-collimated beam transmission, and (4) others. Each amplifier design method is described and the current status of its research is listed in as much detail as possible. By comparing the four types of disk multi-pass amplifiers, it is found that the varying methods have distinct advantages and disadvantages. 4f relay imaging requires a vacuum environment to avoid gas ionization at the focal point, making the mechanics and adjustment more difficult; the resonant cavity design/optical Fourier transform concept multi-pass amplifier has a small spot at the mirrors, making it more suitable for lower energy multi-pass amplifiers; the near collimated beam transmission method has great development potential because it does not require a vacuum environment, but accurately controlling the surface shape of the thin-disk is difficult while the laser is operating. Therefore, from the perspective of laser design, it is necessary to continue to optimize the design of the thin-disk multi-pass amplifier to realize the diversification of application scenarios and the sustainable expansion of output energy.

Chinese Optics
Sep. 20, 2023, Vol. 16 Issue 5 996 (2023)
Recent advances in metasurfaces for polarization imaging
Jun-zhuo ZHOU, Jia HAO, Xiao-chang YU, Jian ZHOU, Chen-wei DENG, and Yi-ting YU

Polarization imaging, a novel photoelectric detection technology, can simultaneously acquire the contour information and polarization features of a scene. For specific application scenarios, polarization imaging has the excellent ability to distinguish different objects and highlight their outlines. Therefore, polarization imaging has been widely applied in the fields of object detection, underwater imaging, life science, environmental monitoring, 3D imaging, etc. Polarization splitting or the filtering device is the core element in a polarization imaging system. The traditional counterpart suffers from a bulky size, poor optical performance, and being sensitive to external disturbances, and can hardly meet the requirements of a highly integrated, highly functional, and highly stable polarization imaging system. A metasurface is a two-dimensional planar photonic device whose comprising units are arranged quasi-periodically at subwavelength intervals, and can finely regulate the amplitude and phase of the light field in different polarization directions. Polarization devices based on metasurface are featured with compactness, lightweight and multi-degree freedom, offering an original solution to ultracompact polarization imaging systems. Targeted at the field of polarization imaging, this paper illustrates the functional theory, developmental process and future tendency of related metasurfaces. We discuss the challenges and prospect on the future of imaging applications and systematic integrations with metasurfaces.

Chinese Optics
Sep. 20, 2023, Vol. 16 Issue 5 973 (2023)
Research progress of miniature head-mounted single photon fluorescence microscopic imaging technique
Qiang FU, Zhi-miao ZHANG, Shang-nan ZHAO, Yang LIU, and Yang DONG

Miniature head-mounted single-photon fluorescence microscopy is a breakthrough approach for neuroscience research that has emerged in recent years. It can image the neural activity of freely moving vivo animals in real time, providing an unprecedented way to access neural signals and rapidly enhancing the understanding of how the brain works. Driven by the needs of brain science research, there have been many types of miniature head-mounted single-photon fluorescence microscopes, such as high-resolution imaging, wireless recording, 3D imaging, two-region imaging and two-color imaging. In order to have a more comprehensive understanding of this new optical neuroimaging technology, we classify its technologies according to the imaging field of view, introduce the characteristics of different types of micro-head-mounted single-photon fluorescence microscopes reported so far, and focus on the optical system scheme and optical performance parameters used. The advantages and disadvantages of different schemes are analyzed and compared and the future direction of development is described to provide reference for the practical application of brain science researchers.

Chinese Optics
Sep. 20, 2023, Vol. 16 Issue 5 1010 (2023)
Recent progress of non-line-of-sight imaging reconstruction algorithms in typical imaging modalities
Lu-da ZHAO, Xiao DONG, Shi-long XU, Yi-hua HU, Xin-yuan ZHANG, and Yi-cheng ZHONG

Non-line-of-sight (NLoS) imaging is a promising technique developed in recent years, which can reconstruct hidden scenes by analyzing the information in the intermediate surface, and "see around the corner", and has strong application value in many fields. In this paper, we review the reconstruction algorithm for NLoS imaging tasks. Firstly, considering the crossover and non-independent phenomena existing in the NLoS imaging classification, we use the different features of physical imaging models and algorithm models to reclassify them. Secondly, according to the proposed classification criteria, we respectively review the traditional and deep learning-based NLoS imaging reconstruction algorithms, summarize the state-of-the-art algorithms, and derive the implement principle. We also compare the results of deep learning-based and traditional NLoS imaging reconstruction algorithms for reconstruction tasks. Finally, the current challenges and the future development of NLoS imaging are summarized. Different types of NLoS imaging reconstruction algorithms are comprehensively analyzed in this review, which provides important support for the further development of NLoS imaging reconstruction algorithms.

Chinese Optics
May. 15, 2023, Vol. 16 Issue 3 479 (2023)
Application of laser in the medical field
Yong-gang GU, Jian NIU, Jian YANG, and Hong-xing XU

With the rapid development of laser technology, the application of laser in the medical field has gained growing attention. Due to its advantages of non-contact, high precision, low damage, portability and operational flexibility, laser treatment significantly enriches the clinical treatment toolkit. Moreover, it has substituted traditional methods for certain diseases and improved the overall medical treatment capability. Currently, laser treatment has gained increasing market share and has a great potential for even more widespread applications. Here, we introduce the laser treatment technique and the requirements of medical laser systems, expound the current status of the applications of laser treatment in clinical departments in a comprehensive manner, and give suggestions regarding to the problems in the laser treatment field in China.

Chinese Optics
Mar. 01, 2023, Vol. 16 Issue 2 283 (2023)
Research progress on high-resolution imaging system for optical remote sensing in aerospace
Yun SU, Jing-jing GE, Ye-chao WANG, Le-ran WANG, Yu WANG, Zi-xi ZHENG, and Xiao-peng SHAO

With the continuous development of optical imaging technology and the growing demand for remote sensing applications, cross-scale high-resolution optical technology has been widely used in the field of remote sensing. In order to obtain more detailed information on the target, domestic and foreign researchers have carried out relevant research in different technical directions. In this paper, through the technical classification of remote sensing imaging, we introduce a representative aerospace optical remote sensing high-resolution imaging system. It focuses on monomer structure, block expandable imaging, optical interference synthesis aperture imaging, diffraction main mirror imaging, optical synthetic aperture and other technologies. It provides a new idea for the development of high-resolution optical remote sensing loads on the ground.

Chinese Optics
Mar. 01, 2023, Vol. 16 Issue 2 258 (2023)
Research progress of temperature, humidity and pressure detection technology using raman lidar
Dong LIU, Qing-rui YAO, Si-nuo ZHANG, Jia-xin GAO, Nan-chao WANG, Jiang WU, and Chong LIU

Atmospheric temperature, humidity and pressure are deemed important atmospheric parameters. Quickly and accurately understanding the temperature, humidity and pressure information of the atmosphere and their changing trends is of great significance to research on meteorology, climatology, and artificial weather research. Raman lidar can obtain various atmospheric environment-related parameters by separating Raman scattering signal inversion, which can achieve high accuracy detection of atmospheric parameter profile information. Raman lidar has unique advantages and potential in atmospheric temperature, humidity and pressure detection. With an introduction to the principle and inverse analysis algorithm of Raman lidar for atmospheric temperature, humidity and pressure detection, this paper also highlights the advantages and disadvantages along with related advances of spectral devices such as filters, etalons and gratings commonly used in Raman lidar. The detection techniques involved in Raman lidar are also included. Finally, typical applications of meteorological parameter measurements by Raman lidar are shown.

Chinese Optics
Mar. 01, 2023, Vol. 16 Issue 2 243 (2023)
Research progress of gas detection based on laser-induced thermoelastic spectroscopy
Cun-guang LOU, Jia-liang DAI, Rui-kai LI, Xiu-ling LIU, and Jian-quan YAO

Laser-Induced Thermo-Elastic Spectroscopy (LITES) is a new developed gas detection technology based on the thermoelastic effect of Quartz Tuning Forks (QTF). The QTF has the advantages of low cost, small volume, high sensitivity and wide spectral response range, and the LITES is becoming a vital method for trace gas detection. In this paper, the basic principle of gas concentration measuring based on LITES is firstly analyzed. Secondly, from the perspective of various technical methods, this paper introduces the methods for improving the sensitivity of QTF detectors, and reviews the research progress of LITES system in recent years. The performance of these systems is evaluated by the signal amplitude, Signal-to-Noise Ratio (SNR), minimum detection limit, and Normalized Noise Equivalent Absorption (NNEA) coefficient. Finally, the practical application of LITES in the field of gas detection technology is briefly reviewed, and the methods for further improving its sensitivity are summarized and prospected.

Chinese Optics
Mar. 01, 2023, Vol. 16 Issue 2 229 (2023)
Design, preparation and application of orthogonal excitation-emission upconversion nanomaterials
Heng JIA, Xiao-rui FENG, Da-guang LI, Wei-ping QIN, Long YANG, Wei-yan HE, Hui-yan MA, and Ying-yue TENG

Rare earth-doped upconversion luminescence nanomaterials have received considerable attention from researchers due to their great potential for applications in many fields such as information security, biomedicine, optical fiber communication, digital displays, and energy. The recently-developed upconversion luminescence nanoparticles with orthogonal excitation-emission properties have attracted especially strong research interest because their distinct luminescence outputs can be dynamically modulated by switching the excitation conditions. The orthogonal luminescence properties further endow such nanocrystals with a set of new features and functionalities, which largely expands their potential applications. This review summarizes the progress in the development of orthogonal upconversion luminescence of rare earth ions, and provides a systematic discussion on design principles and construction strategies of orthogonal excitation-emission systems based on core-shell structures, as well as introduces their recent advances in various fields of applications including data storage, security anti-counterfeiting, digital displays, sensing, bioimaging and therapy. Furthermore, the prospective opportunities and challenges in the future research of orthogonal luminescence systems are also provided.

Chinese Optics
Jan. 20, 2023, Vol. 16 Issue 1 76 (2023)
Research progress of monolithic integration master-oscillation power-amplifiers
Man-qing TAN, Dao-ming YOU, Wen-tao GUO, and Wei-hua LIU

Besides its advantages in volume, power and beam quality, a monolithic integration Master-Oscillation Power-amplifier (MOPA) can also realize a narrower linewidth and dynamic single-mode by integrating Bragg grating. Its application value is high in the fields of frequency doubling, pumping, optical communication and sensing, which makes it a popular research topic in recent years. This paper firstly went over the mainstream structure and characteristics of monolithic integrated MOPA, including a tapered amplifier, ridge amplifier, Bragg grating and three-section MOPA. Based on their working principles and performance characteristics, we introduce the main research directions and the latest development trends in combination with their problems. Aiming at the problem of beam quality degradation at high power in monolithic integrated MOPA, the optimal design of epitaxial layer structure, facet optical film and electrode aspects are then summarized for monolithic integrated MOPAs. After that, we sort out the research progress of MOPAs with different performance characteristics for various application requirements including high power, narrow linewidth, high beam quality and high brightness. Finally, we prospect the development trend of monolithic integrated MOPA.

Chinese Optics
Jan. 20, 2023, Vol. 16 Issue 1 61 (2023)
Panoramic endoscopic imaging technology and it’s applications
Jia-yi HUO, Mian-hao LI, Zi-chuan WANG, Bo YUAN, Qing YANG, and Li-qiang WANG

Panoramic endoscopic imaging technology can effectively reduce the observation blind area of internal organs. It has many advantages, such as shortening the operation time, reducing the risk of intraoperative bleeding, improving the prognosis and shortening the postoperative recovery time. It has important application value in minimally invasive surgery and preoperative examination. It is a research hotspot in recent years. This paper combs the panoramic endoscopic imaging technology from two aspects: principle and product applications. Firstly, various panoramic endoscopic imaging technologies based on two-dimensional and three-dimensional imaging are reviewed, their implementation methods are described, and their key indexes and performances are analyzed. Secondly, the capsule endoscope, panoramic enteroscope and other different types of products derived from panoramic endoscopic imaging technology are compared and analyzed, and the development trend and application prospect of panoramic endoscopic imaging technology are prospected.

Chinese Optics
Jan. 20, 2023, Vol. 16 Issue 1 44 (2023)
Recent progress on synthesis and optical characterization of two-dimensional Bi2O2Se
Bing XIE, Xu-hong AN, Wei-wei ZHAO, and Zhen-hua NI

Two-dimensional (2D) Bi2O2Se has attracted broad attention in the field of electronic and optoelectronic applications in the UV-Vis-NIR region due to its unique crystal structure, energy band, high carrier mobility, and excellent stability. In this paper, we review the recent research progress in the material synthesis and optical characterization of Bi2O2Se. Firstly, the synthetic method and growth mechanism of 2D Bi2O2Se are introduced, including Chemical Vapor Deposition (CVD), wet chemical process, Molecular Beam Epitaxy (MBE) and Pulsed Laser Deposition (PLD), etc. Via steady-state spectrum study, the properties change of 2D Bi2O2Se with thickness change can be studied, such as the band gap. The defect type, temperature coefficient and thermal conductivity of 2D Bi2O2Se material can be further studied by focusing on the crystal vibration mode. Transient spectrum techniques can benefit the study of relaxation process and carriers transport properties in 2D Bi2O2Se materials. Finally, we summarize the existing challenges and application prospects for the promising Bi2O2Se field.

Chinese Optics
Jan. 20, 2023, Vol. 16 Issue 1 24 (2023)
Bound states in continuum in periodic optical systems
Jian-quan YAO, Ji-tao LI, Ya-ting ZHANG, Jie LI, Zhen YUE, Hang XU, and Fan YANG

Periodic optical systems, such as photonic crystals and optical metamaterials, can localize high-density electromagnetic field energy at subwavelength scales and obtain extremely small mode volumes, so they have great application potential in the field of light manipulation. In recent years, a strong interaction between light and matter in periodic optical systems has been discovered, which is called Bound States in Continuum (BIC). Optics BICs are special electromagnetic eigenstates whose frequencies lie in the radiation continuum but are completely localized, and have shown interesting physics and rich application scenarios. This paper systematically reviews the classification and theory of BICs in periodic optical systems, and summarizes their basic physical properties and the latest application development. BICs in periodic optical systems are injecting new impetus into the fields of integrated optics, information optics, bio-optics, topological optics, and nonlinear optics.

Chinese Optics
Jan. 20, 2023, Vol. 16 Issue 1 1 (2023)
Trans-scale optical endoscopy imaging technology
Zi-chuan WANG, Wei ZHANG, Fei GUO, Zhi-qiang JIA, Li-qiang WANG, Wen-fei DONG, and Qing YANG

Due to the advantages of high resolution, multi-scale, multi-dimension, low radiation and easy to integrate, optical imaging technology plays an important role in biomedical field. In the field of endoscopy, how to obtain, process and visualize the endoscopic image information is the core of the problem what optical imaging technology need to solve. The obtaining of trans-scale endoscopic image of patients in the medical clinical is more advantageous to the surgeon for the diagnosis of patients and can improve in accuracy of the operation. The review starts with the application of trans-scale optical imaging technology in the field of endoscopy, focusing on the different optical systems to obtain trans-scale images in clinical endoscopy, including trans-scale optical zoom system, multi-channel imaging system, fiber-scanning imaging system, and expounds its progress and future trends.

Chinese Optics
Nov. 30, 2022, Vol. 15 Issue 6 1287 (2022)
Recent development of cryo-correlated light and electron microscopy
Jing LU, Wei-xing LI, Xiao-jun XU, and Wei JI

Cryo-electron tomography (cryo-ET) has become a cutting-edge technology in life sciences for the investigation of protein complexes directly in their natural state. In cryo-ET, the sample’s thickness must be less than 300 nm and the target molecule must be within the lamella, which is prepared by cryo-Focus Iron Beam (FIB) milling. In order to precisely navigate molecules and to improve the efficiency of sample preparation, cryo-Correlative Light and Electron Microscopy (cryo-CLEM) has been introduced to perform in-situ imaging on the frozen samples. The cryo-CLEM combines the localization advantages of fluorescence imaging with the resolution advantages of electron microscopy. By registering images of light and electrons, frozen samples can be thinned by FIB milling, so the efficiency of cryo-ET sample preparation can be improved. In this paper, we review the latest progress and applications of cryo-CLEM technologies, with a particular focus on super-resolution cryo-CLEM imaging and integrated cryo-CLEM. The advantages and limitations of various methodologies, as well as their application scope, are discussed. A discussion on cryo-CLEM's limitations and potential directions for its future development are also presented.

Chinese Optics
Nov. 30, 2022, Vol. 15 Issue 6 1275 (2022)
Multi-target panoramic digital pathology: from principle to application
Xin-hua ZHANG, Cai-wei LI, Yu ZHANG, Sheng-nan HUANG, Han SHI, Jun-nan WU, Shi-jie REN, Ke-han LIU, Tong-lu GAO, and Bing SHI

Digital pathology has brought new opportunities for remote pathological consultation and joint consultation owing to its convenient storage, management, browsing and transmission. However, because of the limited field of view of a microscope, panoramic imaging cannot be achieved while ensuring a high resolution. The proposal of panoramic digital pathology makes up for this defect and achieves panoramic imaging while ensuring high resolution. However, a single slice can only detect a single target, and disease diagnosis needs to observe the expression of multi-target at the same time. In recent years, multi-target panoramic digital pathology technology has developed rapidly. It has attracted much attention because of its great application potential in drug research and development, clinical research and basic research. Owing to its large field of view, wide range of colors and high flux, the system can detect the expression of various biomarkers on a whole tissue section in situ in a short time to identify the phenotype, abundance, state, and relationship of each cell. Firstly, this paper reviews the development process of digital pathology, panoramic digital pathology and multi-target panoramic digital pathology, as well as the update and iteration of technology in the development process, and illustrates the importance of developing multi-target panoramic digital pathology. Then, the multi-target panoramic digital pathology is described in detail from three perspectives: biological sample preparation, multi-color imaging system and image processing. Next, the applications of multi-target panoramic digital pathology in biomedical fields, such as tumor microenvironments and tumor molecular typing are described. Finally, the advantages, challenges and future development of multi-target panoramic digital pathology are summarized.

Chinese Optics
Nov. 30, 2022, Vol. 15 Issue 6 1258 (2022)
Advances in multi-dimensional single molecule imaging
Meng-fan LI, Jian-wei CHEN, Wei SHI, Shuang FU, Yun-ze LI, Ting-dan LUO, Jun-fan CHEN, and Yi-ming LI

Single-molecule imaging is widely used for the reconstruction of three-dimensional subcellular structures. The point spread function is an important window to analyze the information of a single molecule. Besides 3D coordinates, it also contains abundant additional information. In this paper, we reviewed the recent progress of multi-dimensional single-molecule imaging, including spatial location, fluorescence wavelength, dipole orientation, interference phase, etc. We also briefly introduced the latest methods for molecule localization and proposed the further directions for its research.

Chinese Optics
Nov. 30, 2022, Vol. 15 Issue 6 1243 (2022)
Advances in organic fluorescent probes for super-resolution imaging of cellular lipid droplets
Ri ZHOU, Chen-guang WANG, and Ge-yu LU

Lipid droplets are a kind of spherical organelle in eukaryotic cells and are relevant to many cellular physiological processes. Fluorescence imaging techniques are one of the most powerful tools to visualize and study lipid droplets. However, conventional wide-field microscopy and confocal microscopy can only provide a resolution of about 250 nm due to the limitation of optical diffraction. This resolution is quite insufficient for visualizing the small lipid droplets, especially the nascent ones (size of about 30~60 nm). Emerging super-resolution microscopes that can break the diffraction limit (such as stimulated emission depletion microscopy, structured illumination microscopy and photoactivated localization microscopy) have gradually attracted much interest in recent years. To obtain high-resolution fluorescence images of lipid droplets, the advanced fluorescent probes which meet the special requirements of the corresponding super-resolution microscopes are highly essential. This review paper will briefly introduce the working principles of various super-resolution microscopes, discuss the special requirements on the photophysical properties of fluorescent probes, and systematically summarize the research progress of super-resolution imaging of lipid droplets by employing these fluorescent probes. Meanwhile, this review will compare the advantages and shortcomings of different super-resolution techniques for lipid droplets imaging, and prospect their future possible trends.

Chinese Optics
Nov. 30, 2022, Vol. 15 Issue 6 1228 (2022)
Recent progress on the reconstruction algorithms of structured illumination microscopy
Bo ZHOU, Kun-hao WANG, and Liang-yi CHEN

As an early component of modern Super-Resolution (SR) imaging technology, Structured Illumination Microscopy (SIM) has been developed for nearly twenty years. With up to ~60 nm wavelengths and 564 Hz frame rates, it has recently achieved an optimal combination of spatiotemporal resolution in live cells. Despite these advantages, SIM also suffers disadvantages, some of which originated from the intrinsic reconstruction process. Here we review recent technical advances in SIM, including SR reconstruction, performance evaluation, and its integration with other technologies to provide a practical guide for biologists.

Chinese Optics
Nov. 30, 2022, Vol. 15 Issue 6 1211 (2022)
Large field-of-view optical microscopic imaging technology
Yi-qiang WANG, Fang-rui LIN, Rui HU, Li-wei LIU, and Jun-le QU

With the characteristics of real-time, high-resolution and non-invasive, optical microscopy can scale from cells, tissues to whole living organisms, which has greatly expanded our understanding to the nature of life. However, due to the limited Space-Bandwidth Product (SBP), it is hard for a conventional optical microscope to achieve a large field of view with a high resolution. This makes it very difficult for microscopic imaging in large field of view biological imaging applications, such as imaging of neural circuits between the synapse of the brain neural networks. Recently, large field-of-view imaging technology has received increasing attention and experienced rapid development. The SBP has been improved ten times or even a hundred times as compared to a traditional optical microscope and the field-of-view has been expanded without sacrificing resolution, which, in turn, has resolved some major problems in biomedical research. This review introduces the progress, characteristics and corresponding biological applications of several typical trans-scale optical imaging techniques in recent years, and gives an outlook on their future development.

Chinese Optics
Nov. 30, 2022, Vol. 15 Issue 6 1194 (2022)
Multi-channel multiplexing digital holographic imaging for high throughput
Zheng-zhong HUANG, and Liang-cai CAO

Optical imaging has become the dominant method for characterizing information in biological systems. The rapid, non-destructive and comprehensive characterization of biological samples in recent years has placed high demands on the resolvable volume of imaging systems. Digital holography records an entire complex wavefront including both the amplitude and phase of the light field by interference imaging. Due to fast, non-destructive, and 3D imaging abilities, digital holography has been used in numerous applications such as digital pathology, label-free observation and real-time monitoring of in vitro cells. First, this paper introduces the main ways to achieve high-throughput imaging, and analyzes the advantages of digital holography and the evolution of spatial bandwidth. Secondly, a theoretical framework for high-throughput multi-channel multiplexing digital holography based on the Hilbert transform is presented. Then, an extended field of view digital holographic microscope is introduced based on this theoretical framework. Experimental results indicate that the system achieves 8 times the space-bandwidth product higher than that of conventional off-axis holographic microscopes without sacrificing spatial and temporal resolution. This high-throughput digital holographic multiplexing technology can make full use of the redundant spatial bandwidth of single intensity image, which verifies the feasibility of high-throughput multi-channel multiplexing digital holography.

Chinese Optics
Nov. 30, 2022, Vol. 15 Issue 6 1182 (2022)
In-vivo across-scales two-photon microscopic imaging technique
Shuai CHEN, Lin REN, Zhen-qiao ZHOU, Min LI, and Hong-bo JIA

Two-photon microscopy’s ability to maintain good spatial resolution in thick biological tissues has led to its application in in-vivo brain imaging studies soon after its conception. As neural networks have cross-scale multidimensional spatio-temporal properties, two-photon microscopy has developed rapidly and significantly in recent years to meet the demand for in-vivo cross-scale imaging of the brain. This paper firstly introduces the working principle of two-photon microscopy, then reviews the progress of two-photon microscopy from five perspectives: imaging field of view, imaging flux, imaging depth, resolution, miniaturization, and analyzes the difficulties and future challenges of cross-scale two-photon in-vivo microscopic imaging technology.

Chinese Optics
Nov. 30, 2022, Vol. 15 Issue 6 1167 (2022)
Resolution, super-resolution and spatial bandwidth product expansion——some thoughts from the perspective of computational optical imaging
Chao ZUO, and Qian CHEN

Conventional optical imaging is essentially a process of recording and reproducing the intensity signal of a scene in the spatial dimension with direct uniform sampling. In this process, the resolution and information content of imaging are inevitably constrained by several physical limitations such as optical diffraction limit, detector sampling, and spatial bandwidth product of the imaging system. How to break these physical limitations and obtain higher resolution and broader image field of view has been an eternal topic in this field. In this paper, we introduce the basic theories and technologies associated with the resolution, super-resolution, and spatial bandwidth product expansion, as well as some examples in the field of computational optical imaging. By placing these specific cases into the higher dimensional framework of "computational optical imaging", this paper reveals that most of them can be understood as a "spatial bandwidth regulation" scheme, i.e., a process of exploiting the available degrees of freedom of the imaging system to optimally encode, decode, and transmit information within the constraints of the limited spatial bandwidth of the imaging system, or figuratively speaking - "dancing with shackles". This is essentially a legal trade-off and choice between "gain" and "loss" under physical constraints. The conclusions of this paper are expected to provide valuable insights into the design and exploration of new imaging mechanisms and methods for various complex practical imaging applications.

Chinese Optics
Nov. 30, 2022, Vol. 15 Issue 6 1105 (2022)
Overview of key technologies for segmented mirrors of large-aperture optical telescopes
Yin-long HUO, Fei YANG, and Fu-guo WANG

With the continuous development of astronomical exploration, the aperture of telescopes is getting larger and larger. Segmented mirror technology offers a viable and much simpler alternative to a large single monolithic primary mirrors, and has become an important way of designing the primary mirror of large-aperture telescopes. This paper summarizes the current development status of various technologies with reference to the primary mirror design of typical segmented telescopes such as the JWST and TMT, and elaborates on the performance differences and mirror supports of different segmented primary mirror schemes under the background of large-scale sub-mirrors. Potential future development trends of this technology and co-phasing detection technology are provided. This research acts as a reference for the independent development of the next generation of very large aperture optical infrared telescopes in China.

Chinese Optics
Sep. 22, 2022, Vol. 15 Issue 5 973 (2022)
Survey of non-blind image restoration
Hang YANG

Non-blind image restoration is one of the most improtant research topics in the field of computer vision. It is also a typical ill-posed problem in mathematics. Its goal is to estimate a clear image from a blurred image when the point spread function is known. Its research focuses on how to make an appropriate compromise between improving clarity and suppressing noise. In the past 50 years, non-blind image restoration has made great progress. From the Wiener filtering to deep learning based methods, scholars have proposed hundreds of non-blind image restoration algorithms and applied them in various academic fields. This paper first introduces the basic concept and research significance of non-blind image restoration, then classifies and summarizes the main non-blind image restoration algorithms according to the algorithm attributes, which are generally divided into traditional methods and deep learning based methods. The traditional methods are divided into the direct method and iterative method, then are analyzed for their advantages and disadvantages. The performance of representative restoration algorithms is compared in a varity of typical experiments. Finally, the development trend and important research directions of non-blind image restoration algorithms are proposed.

Chinese Optics
Sep. 22, 2022, Vol. 15 Issue 5 954 (2022)
Research progress of high-speed vertical-cavity surface-emitting laser in CIOMP
Si-cong TIAN, Cun-zhu TONG, Li-jun WANG, and Dieter BIMBERG

High-speed vertical-cavity surface-emitting laser (VCSEL) is one of the main light sources for optical communication. Driven by the rapid growth of data traffic, the high-speed VCSEL is developing towards larger bandwidth and higher bit rate. By optimizing the epitaxy design and the growth of VCSELs, the design and the fabrication of VCSELs, and the high-frequency characterization techniques, much remarkable progress of high-speed VCSELs with different wavelengths have been achieved in modulation bandwidth, transmission rate, mode, power consumption in Changchun Institute of Optics, Fine Machanics and Physics (CIOMP). The research progress of high-speed VCSELs includes: high-speed single-mode 940 nm VCSEL with 27.65 GHz modulation bandwidth and 53 Gbit/s transmission rate; 200 Gbit/s optical link based on 850 nm, 880 nm, 910 nm and 940 nm high-speed VCSELs via wavelength division multiplexing; ultra-low power consumption as low as 100 fJ/bit of high-speed VCSEL via optimization of photon lifetime; 1030 nm high-speed VCSEL with 25 GHz modulation bandwidth; 1550 nm high-speed VCSEL with 37 Gbit/s transmission rate. The developed high-speed VCSELs have important application prospects in optical communication.

Chinese Optics
Sep. 22, 2022, Vol. 15 Issue 5 946 (2022)
Review of physical implementation architecture in compressive spectral imaging system
Yun-hui LI

Different from the traditional point-to-point mapping imaging method, computational optical imaging combines the physical regulation of the front-end optical signal with the processing of the back-end digital signal to make the image information acquisition more efficient. This new imaging mechanism is expected to alleviate the contradiction between low manufacturing cost and high performance indicators under the framework of traditional imaging technology, especially in the acquisition of high-dimensional image information. Since the system architecture supported by physical devices is the cornerstone of computational optical imaging, aiming at the sub-technical field of compressive spectral imaging, in this paper, we introduce the existing optical devices that can realize spatial or spectral modulation. Based on this, the architecture of multi-type compressive spectral imaging system is sorted out and summarized, which can be categorized as single-pixel spectral imaging, coded aperture spectral imaging, spatial-spectral dual-coded spectral imaging, microarray spectral imaging and scattering medium spectral imaging, based on the information modulation process. We focus on the information modulation and acquisition principles of various system architectures and their modulation effects on the spatial-spectral data cube, and then analyze and explore the common issues. Finally, the technical challenges faced are given, and the future development trend is discussed.

Chinese Optics
Sep. 22, 2022, Vol. 15 Issue 5 929 (2022)
Review of ultraviolet photodetectors based on micro/nano-structured wide bandgap semiconductor oxide
Xing CHEN, Chang ZHOU, Ke-wei LIU, and De-zhen SHEN

Ultraviolet photodetection technology is another dual-use detection technology after infrared detection and laser detection technology, which has broad application prospects. Vacuum photomultiplier tubes and Si-based photodiodes are common commercial UV detectors, but vacuum photomultiplier tubes are susceptible to high temperatures and electromagnetic radiation, and need to work under high pressure while Si-based photodiodes require expensive filters. Wide bandgap semiconductor ultraviolet photodetectors have overcome some of the problems faced by the above two devices, and are becoming the research hotspot. Among them, wide bandgap oxide materials have attracted extensive attention, due to the advantages of easy preparation for high response and high gain devices, and rich micro-structures and nano-structures. In this paper, ultraviolet photodetectors based on micro/nano-structured wide bandgap semiconductor oxide are combed, and some related researches in recent years are reviewed. The oxide materials involved include ZnO, Ga2O3, SnO2 and TiO2, etc. and the device structures involved include metal-semiconductor-metal devices, Schottky junction devices and heterojunction devices, etc.

Chinese Optics
Sep. 22, 2022, Vol. 15 Issue 5 912 (2022)
Recent advances in lateral mode control technology of diode lasers
Li-jie WANG, Cun-zhu TONG, Yan-jing WANG, Huan-yu LU, Xin ZHANG, Si-cong TIAN, and Li-jun WANG

High power diode lasers are widely used for pumping solid-state lasers and fiber lasers, material processing, laser radars, free-space optical communication, security and defense. However, conventional diode lasers suffer from large far-field divergence angles, poor beam quality and low brightness, which restricts their direct applications. Broad-Area diode Lasers (BALs) can achieve high output power and efficiency. However, their lateral mode is usually influenced by many physical mechanisms, leading to a large number of guided lateral modes at high-power operation. It results in a rapid increase of the far-field width and strongly deteriorated beam quality, limiting the improvement of diode lasers′ brightness. Therefore, the lateral modes should be carefully controlled. In this paper, the factors influencing the diode lasers′ lateral modes are reviewed, and the lateral mode characteristics, optical field distribution and their relations with the device construction are analyzed. Then, the current lateral mode control technologies are described in detail. The beam quality and brightness of the output beam can be enhanced via the suppression of high-order lateral modes and the far-field blooming effect. As a result of advanced lateral mode control, novel high-brightness diode lasers can be developed at the chip level, which is beneficial for developing new diode lasers applications and reducing their system cost.

Chinese Optics
Sep. 22, 2022, Vol. 15 Issue 5 895 (2022)
Research progress of single molecule biological detection methods and applications
Wen-chao ZHOU, Zheng-hao LI, and Jie WU

Single molecule biological detection technology is an efficient technology to understand the dynamic characteristics of various biomolecules at the single molecule level and explore their structure and function. The advantage of this technology is that it can detect the heterogeneity of free energy on a single molecule, which is beyond the traditional methods. Therefore, researchers use it to solve long-standing problems in complex biological systems, heterogeneous catalysis, biomolecular interactions, enzyme systems and conformational changes. In terms of medical detection, detecting specific information about single molecules or their interactions with biological factors is not only crucial for the early diagnosis and treatment of various diseases such as cancer, but also has great potential for real-time detection and precision medicine. The advantages of high specificity and high precision of single-molecule bioassays are used to real-time detection of single biomolecules in molecular populations, and can be combined with multiple high-throughput analysis for the precise diagnosis of clinical samples. In this paper, the principle of single molecule detection and the application of biosensing are introduced, and the detection methods and related applications are summarized. Finally, the prospect and development direction of this research direction are discussed.

Chinese Optics
Sep. 22, 2022, Vol. 15 Issue 5 878 (2022)
Review of optical systems′ desensitization design methods
Qing-yu MENG, Zi-chang QIN, Cheng-ming REN, and Yun-sheng QI

The effective realization of desired optical system performances depends not only on the design results of imaging quality, but also on the realizability of various tolerances such as optical manufacturing tolerances, assembly tolerances, and environmental tolerances. An optical system with low error sensitivity relaxes tolerance requirements, which can better resist image quality degradation disturbed by errors. While reducing manufacturing costs, it effectively improves the realizability of an optical system, thereby reducing error sensitivity. It is an important link that should be considered in optical system design. This paper analyzes and summarizes the research status of optical system error sensitivity, summarizes typical optical system desensitization methods, and summarizes the application of these methods in optical system design. Finally, potential future development directions for low error sensitivity design methods for optical systems are provided.

Chinese Optics
Sep. 22, 2022, Vol. 15 Issue 5 863 (2022)
Research progress on nonlinear optics of polyvinylidene fluorid and its copolymers films
Yong LIU, Wei-guo LIU, Xiao-ling NIU, Ying-xue HUI, Zhong-hua DAI, Zhi-heng WANG, and Wen-hao GUO

Polyvinylidene fluoride (PVDF) and its copolymers films have been extensively used in photoelectric functional devices such as photoelectric conversion, optical regulation, optical switch. They are the most important polymeric ferroelectricity materials with excellent electro-active properties, high diffraction efficiency and significant nonlinear optical effect. We summarize the progress in nonlinear optical effect of polyvinylidene fluoride and its copolymers films both in domestic and foreign research within the last several years. We illustrate that the development direction of the films will be nanoscale-doping, blending modification and ultrathin. The nonlinear optical properties should be investigated by the first-principle and photonic band gap calculations, and measured by the means of the high sensitivity Z-scan, Marker fringe combing with ellipsometry. This study can provide an insight for the development and utilization for polyvinylidene fluoride and its copolymers films in future.

Chinese Optics
Jul. 15, 2022, Vol. 15 Issue 4 640 (2022)
The principle, performance characterization and research progress of nonlinear optical limiting materials
Ze LV, You FANG, Tiao FENG, Nan ZONG, Yun-fei LI, Shen-jin ZHANG, Zheng XIE, and Qin-jun PENG

Laser protection materials are of great significance in protecting human eyes and optical components from strong laser pulses. Among them, solid optical limiting materials based on the principle of nonlinear optics will be the main carriers for laser protection. This article introduces the research background, working mechanism, parameters and testing techniques of optical limiting materials, and reviews the research progress of various optical limiting materials with practical prospects, including inorganic semiconductor materials, conjugated organic polymers, inorganic metal clusters, carbon nanomaterials, and two-dimensional materials. And the development prospects of optical limiting materials are discussed.

Chinese Optics
Jul. 15, 2022, Vol. 15 Issue 4 625 (2022)
Research progress of optical fiber Fabry-Perot interferometer high temperature sensors
Ai-wu LI, Tian-qi SHAN, Qi GUO, Xue-peng PAN, Shan-ren LIU, Chao CHEN, and Yong-sen YU

The high temperature sensor of the optical fiber Fabry-Perot interferometer has the advantages of small size, a simple manufacturing process, high sensitivity, high temperature resistance and anti-electromagnetic interference, which make it widely used in the aerospace energy industry, environmental monitoring and other fields. Firstly, this paper introduces the sensing principle, sensing performance, sensing characteristics and fabrication method of optical fiber Fabry-Perot interferometer high temperature sensors. Secondly, the temperature, pressure and strain sensitivity and measurement range are summarized and the domestic and foreign research progress and the performance parameters of optical fiber Fabry-Perot interferometer high temperature sensors are summarized. Thirdly, the cross-sensitivity problems of temperature and pressure of optical fiber Fabry-Perot interferometer sensors and it’s solutions, and the high-temperature sensing characteristics of Fabry-Perot interferometers based on different kinds of optical fibers are introduced. Fourthly, according to the recent research progress of fiber Fabry-Perot interferometer high temperature sensors, several fiber Fabry-Perot interferometer high temperature sensors for two-parameter measurement are introduced. Finally, the future development trend and prospect of optical fiber Fabry-Perot interferometer high temperature sensors are prospected.

Chinese Optics
Jul. 15, 2022, Vol. 15 Issue 4 609 (2022)
Overview of 3D point cloud super-resolution technology
Yong BI, Ming-qi PAN, Shuo ZHANG, and Wei-nan GAO

With the development of the computer vision technology, research on recording and modeling the real world accurately and efficiently has become a key issue. Due to the limitation of hardware, the resolution of a point cloud is usually low, which cannot meet the applications. Therefore, it is necessary to study the super-resolution technology of point clouds. In this paper, we sort out the significance, progress, and evaluation methods of 3D point cloud super-resolution technology, introduce the classical super-resolution algorithm and the super-resolution algorithm based on machine learning, summarize the characteristics of the current methods, and point out the main problems and challenges in current point cloud data super-resolution technology. Finally, the future direction in point cloud super-resolution technology is proposed.

Chinese Optics
Mar. 21, 2022, Vol. 15 Issue 2 210 (2022)
Common failure modes and mechanisms in oxide vertical cavity surface emitting lasers
Yu-qi ZHANG, Zhi-yuan ZUO, Qiang KAN, and Jia ZHAO

Oxide Vertical Cavity Surface Emitting Lasers(VCSELs) are widely used in high-speed optical communications. The reliability of VCSELs is a very important index that requires a high lifetime and low failure rate in the application process. Understanding the root causes and mechanisms of VCSEL failure is necessary and helpful to improve device reliability. In this paper, we summarize and analyze the most common failure modes, causes and mechanisms observed in oxide VCSELs from the perspective of design, manufacturing and application, then apply some appropriate measures and suggestions to prevent or improve them. Moreover, the three dominating factors leading to the failure of VCSELs including oxide layer stress, Electronic Static Discharge (ESD) and humidity corrosion are introduced in more detail. At last, we simply introduce the VCSEL failure cases encountered in the actual accelerated aging verification process. This article can be used as a good VCSEL failure analysis library for chip development and production researchers.

Chinese Optics
Mar. 21, 2022, Vol. 15 Issue 2 187 (2022)
Research progress of lithium niobate thin-film modulators
Hai-feng LIU, Hong-jie GUO, Man-qing TAN, and Zhi-yong LI

Electro-optic modulators based on lithium niobate (LiNbO3, LN) thin-film platforms are advantageous for their small volume, high bandwidth and low half-wave voltage. They have important application prospects in the field of optical fiber communication and optical fiber sensing, and thus have became a heavily researched topic in recent years. In this paper, the research progress of the waveguide structures, coupling structures and electrode structures of LN thin-film modulators are reviewed in detail. The fabrication process of a LN thin-film waveguide is summarized, and the performances of different modulator structures are analyzed. Based on SOI and LNOI, a platform modulator is realized with VπL100 GHz. Thin-film LN modulators are better than commercial LN modulators in most aspects. It can be predicted that in the near future, with the further improvement in waveguide technology, thin-film LN will become a popular scheme of LN modulators. Finally, the potential directions for the future of their research are proposed.

Chinese Optics
Jan. 01, 2022, Vol. 15 Issue 1 1 (2022)
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